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The absence of peripheral failure at the end of the EMG task could be attributed to (1) a lower intramuscular pressure allowing a lesser accumulation of metabolites and (2) a slower rate of PCr hydrolysis compared to the torque task.
Although other mechanisms might also be involved, our data suggest that lithium, via inhibition of GSK-3β, triggers a cascade of protective events ranging from the activation of the canonical Wnt pathway to a reduction of APP phosphorylation and thereby a lesser accumulation of Aβ, to a reduction of tau hyperphosphorylation and of glia reaction in the brain of Tg mice.
Simultaneously, an observed lowering of myeloperoxidase activity in hepatic tissue during APC application indicated a lesser accumulation of neutrophils in the liver.
Inhibition of GAPDH is strongly supported by a ~12-fold accumulation of glyceraldehyde 3-phosphate (GA3P), the substrate of GAPDH, and a lesser accumulation of the upstream metabolites glucose-6-phosphate/fructose-6-phosphate (G6P/F6P) in β-lap+FK866 treated cells.
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However, in this study systematic accumulation of both ϕ2 and ϕ6 bacteriophage was observed over time, and to a lesser extent accumulation of one plasmid (fig. 5).
Analyses of corneas removed from SCD patients during transplantation surgery revealed a marked accumulation of unesterified cholesterol and lesser accumulation of esterified cholesterol and phospholipids (McCarthy et al., 1994; Gaynor et al., 1996; Yamada et al., 1998), suggesting dysregulation of cholesterol metabolism may underlie pathogenesis of the disease.
They differ from Inceptisols, another soil of recent origin, by a lesser subsurface accumulation of transported clay.
To a lesser extent, accumulation of SUMO-1 is also observed.
Lesser accumulation of L-PPI in kidneys was suggestive of its lesser excretion.
In contrast, local-scale controls on channel geometry are more important in the other sub-catchments where lesser accumulation of PSA reflects differences in land clearance.
The exogenous ABA treatment results in high accumulation of thermostable dlps in rye, lesser accumulation in wheat and has no effect in maize.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com