Sentence examples for a lentivirus coding for from inspiring English sources

hAFSC, transduced with a lentivirus coding for luciferase, showed stable expression of the transgene over many population doublings.

To document the specificity of this effect, CLDN4 was stably re-expressed in the CLDN4KD cells by infecting them with a lentivirus coding for a CLDN4 mRNA containing 6 mutations that did not alter the amino acid sequence but abrogated recognition by the shRNAi to create the CLDN4KD/rescued cells.

We have previously developed a lentivirus vector (LV), GLOBE, coding for the human beta globin gene and showed that transplantation of GLOBE-transduced HSCs corrects thalassemia in murine models.

We constructed a lentivirus system encoding for a highly releasable secretion signal peptide, the peptide linked Ex-4 (SP-Ex-4) gene.

He landed a job coding for L. L.

To further test if this system could be used in lung tissue, a bifunctional lentivirus vector that coded for Cre recombinase and a CRISPR/ Cas9 system that targeted PTEN, Nkx2.1, and Apc were generated, and were transfected to the lungs of KP mice; for each targeted gene, tumor burden and grade increased.

They will then infect the neurons with a lentivirus that contains a gene for a specific GFP-tagged synaptic marker, and then let the neurons grow over several weeks until synapses develop and the marker is properly localized.

and the siRNA constructs were introduced to a lentivirus vector plasmid and used for transfection of NRCMs.

Infection was carried out using five lentivirus clones carrying DNA sequences coding for shRNA compatible with hGPR39, or scrambled sequences, at the multiplicity of infection of 5. Twelve hours post infection the medium was replaced with growth medium and 48 h later cells were selected for 14 20 days with 5  μg/ml puromycin, replacing the medium every 3 days.

Bluebird's treatment uses a modified HIV virus, known as a lentivirus, to replace the defective gene for beta globin in the blood-producing stem cells found in these bones.

The provirus genome of SRLVs is typical of lentiviruses, composed of three genes coding for structural proteins: gag, pol and env, an additional three genes, which encode for non-structural proteins: tat, rev and vif and a non-coding long terminal repeat region (LTR) composed of U3-R-U5 [ 4].