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The study of isolated alleles at the six-rowed spike locus has resulted in a leap in the understanding of barley domestication.
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We expect that an iterative process, from genome analysis to model construction will eventually lead to a leap in understanding of the metabolic and ecological capabilities of bacterial species and to advanced eco-systems biology.
This research is not only a leap in our understanding of how and where antibodies work, but more generally in our understanding of immunity and infection".
We also demonstrated that BV leads to a downregulation of ROS-mediated HIF1- α, leading to decreased angiogenesis in vivo, and providing a significant leap in the current understanding of angiogenic pathways hinging on haeme oxygenase activity and carbon monoxide.
One of the first published examples of immuno-EM also marked a major leap in our understanding of the endo-lysosomal system; i.e. the identification of the early endosome as sorting device.
The incredible leap we have faced in the understanding of the basic mechanisms of RNAi has brought a solution for most of the harmful effects identified previously, e.g., a 2′-OMe backbone modifications to prevent off-target effects.
The GEMS study offers a quantum leap in our understanding of the burden and etiology of diarrhea afflicting infants and young children in developing countries.
Provision of this data will generate a major leap in our understanding of the mechanism of translocation and facilitate the reconciliation of divergent biochemical observations.
Explicit recognition of the immense value of information from such initiatives could facilitate a quantum leap in our understanding of the ecological and evolutionary responses of agro-ecosystems.
This has led to the robust identification of more than 500 loci associated with common human diseases, representing a huge leap in our understanding of the aetiopathogenesis of human disease (Hindorff et al. 2009; Manolio et al. 2009).
He thought that providing a way of "seeing" Darwin's ideas in action would create a leap in public understanding.
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