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The phrase "a layer of slime" is correct and usable in written English.
It can be used to describe a thin coating or film of a viscous substance, often in a literal or figurative context.
Example: "After the rain, the rocks were covered with a layer of slime that made them slippery and dangerous to walk on."
Alternatives: "a film of slime" or "a coating of slime".
Exact(6)
A layer of slime, in some species similar to saliva or mucus, covers the whole plasmodium.
Some, though, dismiss it as a glorified duck pond and as I'd been warned about a layer of slime on the water's surface, I abandoned my usual Neddy Merrill-style "choppy crawl" for a head held high breaststroke.
Characteristically, the entire plasmodium is covered by a layer of slime, which is continually secreted and, as the plasmodium creeps, continually left behind as a network of collapsed tubules.
It didn't take long for someone to figure out that the big Victorian house featured in Sunday's season finale of "Mad Men" — as a shaggy Depression-era brothel in one pivotal scene, with the more intense desperation of late-1960's poverty clinging to it like a layer of slime in another — doesn't look like a haunted house in real life.
And just like a real snail leaving a layer of slime across your garden path, this snail leaves a phosphorescent glow as it goes about its journey.
The fruit bodies are medium-sized, pure white, and when wet are covered in a layer of slime thick enough to make the mushroom difficult to pick up.
Similar(54)
But when the diet contains too much starch and too little roughage, rumination all but stops, and a layer of foamy slime that can trap gas forms in the rumen.
My eyelids crack through a layer of sleep-slime and push open.
The fruit bodies (mushrooms) produced by the fungus are characterized by a chocolate to reddish-brown cap covered with a sticky layer of slime, and a short whitish stem that does not have either a partial veil or prominent dark or colored glandular dots.
A glance inside the classrooms reveals the damage the murky waters left behind: Wide cracks and holes have opened in the concrete floor, which is covered in a thick layer of slime.
Fish have a protective layer of slime on their bodies, and will become sick if this "suit of armor" is breached.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com