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These changes were associated with higher osteoclast number and surface in PPARβ−/− vs PPARβ+/+ mice (Supplemental Table 1), whereas the bone-forming indices were lower, particularly at the periosteal surfaces at a latter age.
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A quarter of those in the latter age group, and a fifth of 65-75-year-olds 65-75-year-olds 65-75-year-olds 65-75-year-oldsthave opposedle between 25 and 34.
As shown in Table 4, the odds ratio for patients aged 36-60 years versus patients aged 20-35 years is 0.254, which means that the odds of death for a patient in the latter age group is approximately four times (1/0.254) greater than that for patients in the former age group (p = 0.0029).
All the QRISK2 prediction models show good agreement across the age groups, with a small divergence observed towards the latter age ranges (75 to 85 years).
In this analysis, the latter age group undergoes a switch from TIV to QIV and children aged 2 17 years undergo an analogous switch from the trivalent formulation of LAIV to the quadrivalent formulation of LAIV (QLAIV).
Trends in those aged <1 to 14 years and 15 to 24 years were mostly steady over time, but males had a larger decline than females in the <span class="lh">latter age group between 1968 and the mid-2000s.
Estimates of excess mortality and plots of baseline trends were determined separately for the age groups 65 74, 75+ and 45 64 years (the latter age group being 'unexposed' to a change in vaccine policy or coverage over the period).
The latter age estimate was employed in a recent phylogenetic analysis among the microgastroid genera [ 61]; however, it has been considered as doubtful by Perkovsky et al. [ 62] because it was calculated based on an insufficient layer sampling.
Though only slightly overlapping, the latter age estimate would be congruent with an origin of the derived lineages in an emerging Lake Tanganyika, estimated at 9 12 mya [ 43].
Mice in the latter age group were assessed for seizure vulnerability with a low dose of pilocarpine given 2 h before euthanasia.
Due to the low sample size in the latter age range, post-pubescent subjects/teens were not split into a separate category.
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CEO of Professional Science Editing for Scientists @ prosciediting.com