Sentence examples for a later replication from inspiring English sources

In contrast, an early replicating domain shifted to a later replication timing following neocentromere formation within it.

However, a higher proportion of CpG-island promoters become hypermethylated in genes that change to a later replication timing (n = 52, 18%) relative to hypermethylated CpG-island promoters that change to an earlier replication timing (n = 12, 11%).

Both domains shifted to a later replication timing after neocentromere formation.

Interestingly, in the second study, neocentromere formation caused sequences adjacent to the CENP-A domain to shift to a later replication timing.

The next most common pattern shows the acquisition of lamina association in LNCaP, a change to later replication and hypomethylation across the new LAD (Rank 3; 6.9%, Supplementary Figure 8b, example Fig. 4d).

Here we show that the compact foci of satellite sequences expand in conjunction with their replication and that a satellite sequence, 359-bp, shows a particularly marked shift to later replication in the cell cycle after the midblastula transition (MBT).

Similarly, we find that genes that change to later replication timing are associated with a more repressive promoter environment, characterised by concordant depletion of H3K4me3 and enrichment of H3K27me3.

In contrast, LADs that are either 'lost' or 'gained' in the cancer cells show a change in their replication timing program to earlier or later replication, respectively (Supplementary Figure 8a).

Compared to a random distribution of similarly sized regions, we find LREA domains are significantly distributed towards earlier replication and conversely, LRES domains are significantly distributed towards later replication in the cancer cells (Fig. 4e).

Therefore, these observations hold on in the analyses with the data of the first original study and the later replication study separately, making the observed association between plasma HO-1 concentrations and New-T2DM more convincing.

These materials were developed to be readily reproduced and not require extensive training for use, with the hope that this would facilitate later replication of the model in other primary care settings.