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Heterogeneity was reported using the I index, where a larger score indicates a greater proportion of the variability could be attributed to heterogeneity.
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The four item scores per dimension were added and transformed into values between 0 and 100 points, with a larger score indicating a better quality of life.
The total scores ranged from 36 to 78; larger scores indicate a greater impact.
Each question was scored individually with 1 to 5 points, where larger scores indicate noticeable difficulties, resulting in a total of 15 to 75 points.
A total symptom severity score (ranging from 0 to 51) is derived with larger scores indicating greater symptom severity.
The total scores ranged from 36 to 78; larger scores indicate greater impact.
Finally, the overall DREAM4 score was defined as the average, over the five PDZ target sequences, of the negative <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0012787.e176.PNG" class= inline-graphic"/> -transformed P-values, where larger scores indicated greater statistical significance of the prediction.
Larger scores indicate fewer functional limitations.
The two alternatives (shared or independent model) can then be compared, with larger scores indicating more pronounced differences between the conditions (Table S7).
Then, the genes were ranked according to the combined scores with a larger score value indicating a potentially higher correlation between the gene and nicotine addiction.
A large score value indicates the PSM is more likely to be correct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com