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Discover LudwigThe phrase "a large volume in" is correct and usable in written English.
It can be used when referring to a significant amount or quantity of something within a specific context or field.
Example: "The research paper discusses a large volume in the field of renewable energy sources."
Alternatives: "a significant amount in" or "a considerable quantity in".
Exact(6)
"The meat industry has gotten so huge and producing meat at such a large volume in these huge slaughterhouses it's easy for meat to become contaminated," said Navis Bermudez of the Sierra Club.
The spatial location of the hydrogen-bond donors and acceptor sites was nearly coincident for all poses, but this was not the case for the hydrophobic site that occupies a large volume in the ATP-binding site.
In addition, by generating a large volume in the nucleus with apparently no RNA polymerase II activity, the nucleolus creates a domain of retention/sequestration of molecules normally active outside the nucleolus.
More importantly, the elimination of chloroplasts, which usually occupy a large volume in autotrophic cells, will presumably provide a lot of space for the accumulation of lipid bodies in heterotrophic cells (Additional file 2 Figure S10).
It is possible that under our in vitro conditions (in which there is a large volume in the attractant well, which is unlikely to be depleted during the time scale of the experiment) the scavenging function could actually increase chemotactic responses by reducing the amount of CXCL12 that leaks past the cells into the buffer side, and thereby maintaining a steeper gradient [ 51].
In order to develop protocols rapidly and efficiently for the cryopreservation of large volumes it is necessary to develop and validate a scale down method to emulate the process of ice formation that occurs within a large volume in comparison to that within a standard cryovial.
Similar(54)
All structures had a larger volume in males than females over the whole age range, except for the cerebellum that had a sexually dimorphic developmental trajectory.
A growing appetite for green bonds is prompting issuers to release a larger volume in Europe, the US, Canada and elsewhere – although the product itself is only six years old and there is no index yet to track their performance.
Triton X-100 molecules have a larger hydrophilic part compared with CTAB ones (Table 1), so they occupy a larger volume in the limited nanoreactor where the synthesis process takes place.
In addition, we found that ASD adolescents had a larger volume in the medial prefrontal cortex but a smaller volume in the lingual cortex.
Alternatively, some choose to use thicker sections (e.g. 500 nm) at the expense of lower resolution in order to leave a larger volume in which the CNT can remain undisturbed [ 8].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com