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The phrase "a large variation between" is correct and usable in written English.
It can be used when discussing differences or discrepancies between two or more items, groups, or data points.
Example: "There is a large variation between the test scores of the two classes, indicating differing levels of understanding."
Alternatives: "a significant difference between" or "a considerable disparity between".
Exact(60)
There was a large variation between the amounts.
Quite a large variation between diet groups and seasons were registered in condition factor.
An investigation of 12 different test series from five different producers clearly indicates a large variation between different production series.
The mean number of species per site decreased from 30 to 24, with a large variation between sites.
On average, eleven percent of a practice's cost goes to patients with low income, but there is quite a large variation between practices.
As shown in these tables, there is a large variation between predicted and experimental values; therefore, optimization has been applied on model parameters to minimize this variation.
While there is a large variation between proposed IGRF-11 SV candidate models, the coefficients derived from the steady flow model are within the range of most of the candidate models, indicating it is not an unreasonable estimate.
As can be clearly seen, there is a large variation between the results on the detection accuracy, that indicates a subtle mixing of emotions leading to overlap in classes.
Bishara et al. [25] reported that although there was no statistical difference between the groups treated with home and in-office whitening and the no whitened group, there was a large variation between the data.
The average half-life of FVIII in adult haemophilia A patients is 12 h, but a large variation between individuals (6 29 h) has been observed [6], [7].
In humans and other animals, the MMN amplitude and latency have been shown to be dependent on the magnitude of stimulus deviance [14]; a large variation between standard and deviant stimuli evokes a larger MMN amplitude.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com