The phrase "a large time frame" is correct and usable in written English.
It can be used when discussing durations or periods that are significantly extended or broad in scope.
Example: "The project requires a large time frame to ensure thorough research and development."
Alternatives: "an extended time period" or "a significant duration".
Greg Robinson not only offers a bold new understanding of these events but also studies them within a larger time frame and from a transnational perspective.
On a larger time frame, genome expansion in E. coli, which is significantly associated with the acquisition of virulence factors, appears to be independent of selective forces operating on the core genome.
Although 'pre-clinical' disease can represent a relatively large time frame, it is less clinically relevant from a therapeutic/intervention perspective.
Even from the start, comparisons of genomic sequence in orthologous regions of different grass species examined a very large time frame, such as rice versus sorghum [17] or rice versus various Triticeae [28, 37, 26], all comparisons where the investigated species last shared a common ancestor ~50 mya.
One main cause is that time dynamic costs are rarely taken into consideration sufficiently even though they have a major impact on the final quotation due to the large time frame between the moment of the initial quotation and the actual production start.
The switching cost can be tracked down to the large time frame required for the configuration change and the time needed for finishing the hybrid automatic repeat request (HARQ) processes [3].
Despite this setup, the multitude of centers included and the large time frame carry with them the potential for selection bias in such a non-monitored data collection endeavor.
Large time frames probably helped logistics minimize transportation costs, but they made it hard for stores to plan resources to handle deliveries.
Diffusion-controlled mass removal from both the matrix and from the hydraulically inaccessible zones within the fracture itself result in extremely large time frames for significant mass removal from these systems.
Coevolution of interacting proteins, in large time frames, has been intensively studied and is typically based on the evolutionary distances across different species (Moyle et al. 1994; Pazos and Valencia 2001; Goh and Cohen 2002).
