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The phrase "a large system" is correct and usable in written English.
You can use it when referring to a system that is extensive in size, capacity, or complexity, often in contexts like technology, biology, or organizational structures.
Example: "The research team is studying a large system of interconnected ecosystems to understand the impact of climate change."
Alternatives: "a vast system" or "an extensive system".
Exact(57)
He said such problems were inevitable in a large system.
But the changes in such a large system are complex.
"There are all kinds of complexities in operating a large system," he said.
A macrocosm/microcosm analogy sees similarities between a small system and a large system.
Since the substructures couple the circumferential modes, a large system of equations must be inverted.
The result is a large system of convection-diffusion equations with stiff source terms.
After spacial discretization we obtain a large system of time-convolution equations.
This yields a large system of equations with a particular structure.
However, it turns out that the microbial community in such a large system is impressively resilient.
He argued that they are morphosyllabic in nature, meaning they constitute a large system of syllables, albeit imprecise, while also conveying meaning.
Similar(1)
A large system will typically be used and maintained for some 5 to 10 years or even longer.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com