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The phrase "a large subgroup of" is correct and usable in written English.
It can be used when referring to a significant portion of a larger group that shares certain characteristics or traits.
Example: "A large subgroup of the population prefers to work remotely rather than in an office setting."
Alternatives: "a significant portion of" or "a major segment of".
Exact(41)
Conclusion: APC resistance determined by this functional test is present in a large subgroup of formerly pre-eclamptics.
The tendency to treat a large subgroup of bipolar patients with AP medications for mood stabilization (even without a history of psychosis) essentially provided a naturalistic behavioral psychopharmacology manipulation.
The second class, CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASES (CRKs), has a typical configuration of two DUF26 in the extracellular region and forms a large subgroup of RLKs in plants.
The implemented clinical decision rule reduced the probability of AA in a large subgroup of patients with negative or inconclusive US results [37].
Second, we performed all analyses on a large subgroup of patients admitted after elective cardiac surgery of which we could assume most of the postoperative electrolyte disturbances were caused by intraoperative fluid manipulations.
LRR-RLK is a large subgroup of the rice RLK family, of which, XA21, XA3/XA26 and OsSERK2 have been reported to regulate plant immunity against Xoo, the causal agent of bacterial leaf blight.
Similar(19)
Using data at 24 hours, a larger subgroup of 81 patients that largely encompassed the 47 baseline subgroup patients had a similar enrichment profile.
Earlier, I mentioned the desire to see a larger subgroup of bioengineers as members of our society.
Clinically, a larger subgroup of patients with longstanding diabetes suffers from severe gastrointestinal symptoms, which could indicate an overall hyperalgesia or allodynia of the internal afferents.
In opposition, our data does not support the use of CRP in outcome prediction in critically ill patients, however, in comparison with Ho et al. data, our population had higher APACHE II, SOFA scores and TISS-28 as well as a larger subgroup of patients with documented infection.
Inside the second group twelve alleles of Bcc formed a large subgroup; two alleles of Pandoraea pnomenusa were closely related to this subgroup.
More suggestions(16)
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a significant subgroup of
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a large time of
a large square of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com