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Discover LudwigThe phrase "a large spindle" is correct and usable in written English.
It can be used to describe a spindle that is of considerable size, often in contexts related to textiles, machinery, or crafting.
Example: "The weaver selected a large spindle to accommodate the thick yarn she was using for her project."
Alternatives: "a big spindle" or "a sizable spindle".
Exact(3)
But the sight of a man shaving lamb from a large spindle prompts us to rally.
In addition, a large spindle cell clone (LM38-D2) was established by dilutional cloning of the low-passage MM38-LP cells.
However, chromosome segregation was robust to decreases in spindle size indicating that spindle architecture remained viable and a large spindle is not essential for division of large cells.
Similar(57)
In the top row, MCAK/KLP-7 was also depleted, creating a larger spindle.
A larger spindle may therefore resist rotation, especially given the highly viscous cytoplasm and the relatively short metaphase duration in blastomeres.
Another frequent defect was the presence of a large bent spindle, showing a bundle of microtubules present on only one side of the nucleus (Fig. 6, bottom panel).
The main one (47%), probably corresponding to the previously characterized large spindle myoepithelial cell compartment, was hypertetraploid with a DNA index of 2.75 (relative to 5.6 pg of DNA content in G1 somatic mouse cells).
In addition, small muscles, required for fine motor control, have large spindle densities, whereas those recruited for rapid movement need comparatively a lower spindle density [ 21, 22].
The 1974 three-metre-tall bronze called Large Spindle Piece is on long loan from the Henry Moore Foundation.
Single-cell cloning by limiting dilution of the heterogenous LM38-LP cell line resulted in the initial isolation of several clones of the large spindle cells with large nuclei, as well as some clones of small spindle cells and a few clones forming epithelium-like islets.
LM38-LP large spindle cells surrounding the islets showed remarkable fibrillar cytoplasmic staining for α-SMA and moderate to low staining for pan-CK (Fig. 1, top panels) but were poorly positive for vimentin (data not shown).
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