Sentence examples for a large simplification from inspiring English sources

A potential problem with this approach is that it will be dependent on the thresholds used in peak finding, and it also models average transcription factor binding in a cell population as on-off events, which is a large simplification.

Because the discussed model only addresses the overall PPI network evolution, the more detailed features of this process, i.e., the fast asymmetric functional divergence of duplicated genes [ 28] or the modular preferential attachment [ 18] were disregarded, offering a large simplification with no loss of prediction ability.

This is, of course, a great simplification.

Computational modelling of this setting (multiple cell populations with heterogeneous biophysical and biochemical coupling) is challenging, and still based on a large degree of simplification.

Even with such simplifications, a large number of phenomenological kinetic parameters are introduced in the governing model equations, which must be estimated from available sparse in vivo experimental data.

It is a hypothetical simplification of a large 400 kV transmission system.

The major aim of Principal Component Analysis (PCA) is the orderly simplification of a large number of inter-correlated measures to a few uncorrelated representative constructs or factors [ 47].

We claim the chosen value of 0.1% for the significance level is not critical, either, since the work flow terminates after the same number of simplification steps for a large range of values, which can be seen as follows.

Despite these simplifications, the model exhibits a large range of emergent shore profile shapes.

Admittedly, our model is a simplification in that it assumes a large homogenous mixed population, non-overlapping generations, selection acting only at the haploid stage and more.

The institute has called for a mix of U.S. subsidies, tax credits, loan guarantees, procedural simplifications and institutional support on a large scale.