The phrase "a large set of unknown" is not correct in standard written English.
It seems to be missing a noun after "unknown" to clarify what is being referred to, such as "unknowns" or "unknown factors."
Example: "In the experiment, we encountered a large set of unknowns that complicated our analysis."
Alternatives: "a significant number of unknowns" or "a vast array of uncertainties."
We applied the model to a large set of proteins of unknown function, and predicted functions for thousands of these proteins ranging from general to very specific.
Haustoria ESTs included a large set of unique sequences of unknown function.
Because of incomplete data, imprecise information concerning the interaction mechanisms and the large set of unknown parameter values; reverse engineering of the gene regulatory network is by far a straightforward task [ 8].
This method can be applied to a large set of short coding sequence with unknown function yet found in the streptococcal genomes [ 13].
This study, that included a global expression profiling of miRNAs across a large set of tumors, demonstrated that miRNA expression profiles can be used to classify human cancers of unknown origin.
To localize unknown targets, most template-based methods require a large set of well-engineered templates.
The method is developed and benchmarked on a large set of complete bacterial genomes with annotated pathogenicity, and also applied for the prediction of organisms with unknown pathogenicity.
Whether PPARβ/δ, another PPAR subtype, which has partially overlapping functions as PPARα and is known to share a large set of common target genes with PPARα, also regulates OCTN2 and carnitine transport in cattle is currently unknown.
These data consisted of 237 populations studied by Pemberton et al. (2013), excluding from a larger set of 267 the populations with unknown or ambiguous geographic assignments, populations with sample size ≤5, and populations from Micronesia and Samoa, for which Ashraf and Galor (2013) did not provide values of the economic variables.
However, since including all sources of predictions allowed us to perform the comparison using a larger set of both 'unknown' and non-'unknown' literature-based annotations (data not shown), we included all sources in our further analyses.
