The phrase "a large scale problem for" is correct and usable in written English.
It can be used when discussing issues or challenges that affect a wide area or a significant number of people or systems.
Example: "Climate change is a large scale problem for many countries, impacting agriculture, health, and economies."
Alternatives: "a widespread issue for" or "a significant challenge for".
Examples are taken from research on volatile organics and for a large scale problem: hazardous waste sites.
Physical and emotional abuse of children is a large scale problem in South Africa, with severe negative outcomes for survivors.
For a large-scale problem, a near-optimal solution to the problem is found by two-stage heuristic algorithms based on a neighborhood search method.
Together with the metaheuristic optimization approaches, the methodology overcomes the well-known computational difficulty of Nash equilibrium search, particularly for a large-scale problem.
Using this solution method for a large-scale problem will increase the number of variables to a too large set, so that the exact method would not be useful in this situation and it is hard to obtain optimal solution.
The critics said that the report gave an incorrect impression that air pollution was not causing any large-scale problems for forest ecosystems.
Therefore, all the mentioned algorithms run in polynomial times and can yield a result for large scale problem in practical time periods.
In this paper, we solve the large-scale problem for exterior acoustics by employing the concept of fast multipole method (FMM) to accelerate the construction of influence matrix in the dual boundary element method (DBEM).
It was shown that the proposed method was as accurate as the literature methods for small scale problems, but performed better for large scale problem applications.
In order to improve the efficiency and accuracy of RSM, especially for nonlinear and large scale problems, a coupled BBNS strategy was suggested for drawbead optimization.
