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The phrase "a large scale in" is correct and usable in written English.
It can be used when discussing something that is extensive or significant in size, scope, or impact, often in contexts like research, projects, or events.
Example: "The study was conducted on a large scale in multiple countries to gather diverse data."
Alternatives: "a broad scope in" or "a significant extent in".
Exact(56)
Vanilla is grown on a large scale in the southeast.
State was the first to test tranquillizers on a large scale, in 1954.
The fruit is grown on a large scale in the vicinity of Istanbul.
Only a small number of ketones are manufactured on a large scale in industry.
The government shelled on a large scale in three no-fire zones.
The work premiered in Tokyo in 2006, but has never before been seen on a large scale in Britain.
"It's that we've not yet fully understood, despite huge research efforts, what works on a large scale in middle schools".
Similar(4)
A large-scale in situ experiment was conducted at the Kamaishi mine, Japan.
But Le Roy was the first case to unfurl, on a large-scale, in the age of social media.
Several species are now in culture on a large-scale in east Asia.
And from 2005, vaccination against HFRS began on a large-scale in Huludao with about 100,000 people annually vaccinated.
More suggestions(20)
a major scale in
a large magnitude in
a significant scale in
a massive scale in
a substantial scale in
a huge scale in
a broad scale in
a large proportion in
a vast scale in
a wide scale in
a considerable scale in
a broader scale in
a large stake in
a large imbalance in
a large improvement in
a large variation in
a large expansion in
a large growth in
a large area in
a large majority in
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com