Building a large-scale expert system involves creating and extending a large knowledge base over the course of many months or years.
Whereas the structure of malarial ribosomal RNAs has attracted considerable attention and has been analysed in many comparative studies, no census of ribosomal proteins was undertaken in the first large scale expert annotation of P. falciparum [ 4, 31] and annotations have not been seriously revised since.
The intensifying development of waterless dyeing processes has the potential to change things if the technologies are adopted on a large scale, textile experts say.
"It must be stressed that there was no real masterplan for Red Vienna's building programme, beyond the decision to produce housing on a large scale," says housing expert Michael Klein from the Vienna University of Technology.
On an even larger scale, experts cite a lack of money as endangering a program to slow or halt the destruction of tropical forests at human hands.
"We have never conducted a systematic hunt for weapons of mass destruction in a combat situation on such a large scale," said one weapons expert who has studied the reports filed by the site survey team working at Najaf.
We conducted a large scale approach aimed at the identification, expert annotation and phylogenetic analyses of T3E from the RSSC, a species complex showing considerable genomic diversity [ 10, 11] and responsible for one of the most devastating bacterial disease of plants worldwide [ 2].
We add to the literature on journal classification by providing for the first time a large scale test of the robustness of expert-based classification.
"They have almost inadvertently created a whole ecosystem that's easy to abuse for cyber crime on a large scale," said Dr Gilbert Wondracek, a computer security expert from the International Secure System Lab, which led the study.
Sam's Club officials say they are among the first to offer individualized discounts on such a large scale, an assertion supported by several industry experts.
Such a large scale "central work conference" had not been held since 1988, political experts said.
