The phrase "a large scale effect in" is correct and usable in written English.
It can be used when discussing significant impacts or consequences within a specific context or field.
Example: "The researchers observed a large scale effect in the population's behavior following the introduction of the new policy."
Alternatives: "a significant impact in" or "a widespread effect in".
Addition of higher levels of FIXa have a large-scale effect in aPTT, and have not been plotted so as to preserve the scale of the plot.
We are interested in large scale effects.
The study supports the initiation of a large scale study on the effect of Paleolithic diet in subjects with type 2 diabetes.
Gardner & Schunk [6] used a high-resolution global thermosphere-ionosphere model to examine the effect a large scale perturbation (in this case a pulsating geomagnetic storm) has on the atmosphere.
Of course community service is needed to help run and operate federal programs but only the government has the means to sponsor and initiate projects that will have a significant effect on a large scale in American society.
We have developed a method that integrates 3D structural similarity, protein interactions and adverse effects, in a large scale multi drug-target-adverse effect predictor with novel implications in drug repurposing and patient safety.
Such comparisons will provide needed opportunities to evaluate the responses of biodiversity to larger scale effects of human impacts and climate change in coastal ecosystems.
If the implicit and explicit treatment criteria are applied on a larger scale, underestimation of effects may occur in some herds, overestimation in others.
We hope that this work can provide insights to tackle the challenging problem of assessment of combinational drug therapy effect in a large scale signaling pathway.
We do not observe any large-scale effect of germ line generation time in our dataset, with only 1 protein (Ph20) with evidence of long branch attraction.
The shake flask system also captured particle aggregation effects seen in a large scale stirred vessel, reproducing the fine particle size distribution that impacts the final centrifugal clarification stage.
