The phrase "a large scale determination" is correct and usable in written English.
It can be used when referring to a decision or conclusion that is made based on extensive analysis or evaluation, often involving significant data or a broad context.
Example: "The researchers conducted a large scale determination of the environmental impacts of the new policy."
Alternatives: "a comprehensive assessment" or "a wide-ranging evaluation".
This would allow assessment of predictive robustness on a larger scale, determination of potential associations with treatment response as well as facilitate studies of relevant subpopulations of tumour cells with the possibility of correlating results to clinical parameters.
The present study has provided a large-scale determination of the type-specific HPV prevalences in Finland and their relative contribution to the cervical disease burden.
Although proteomics data has allowed large scale determination of protein localization for model organisms [ 2, 3], no experimental evidence is available for the vast majority of organisms.
Thank you for submitting your work entitled "Large scale determination of previously unsolved protein structures using evolutionary information" for peer review at eLife.
The following dataset was generated: Ovchinnikov S, Kinch L, Park H, Liao Y, Pei J, Kim DE, Kamisetty H, Grishin NV, Baker D, 2015, Data from: Large scale determination of previously unsolved protein structures using evolutionary information, http://dx.doi.org/10.5061/dryad.987j0, Available at Dryad Digital Repository under a CC0 Public Domain Dedication.
No nation has ever changed the planet so rapidly, on such a large scale, and with such single-minded determination.
Another challenge of attempting a large scale evaluation of our hypothesis would be the high-throughput determination of the FAE activity.
The aim will be achieved by a focused, large-scale determination of protein structures by X-ray crystallography and nuclear magnetic resonance spectroscopy, combined efficiently with accurate protein structure modeling techniques.
The recent literature has seen a significant increase in the number of publications that attempt the determination of protein abundances in yeast cells on a large scale [1] [4].
The reported results will be used in the optimization of preparative chromatography such as SMB chromatography after the determination of the adsorption isotherms in later work for a large scale.
Recent advances in experimental high-throughput (HTP) approaches allowed the determination of protein interaction partners in various organisms on a large scale.
