The phrase "a large role of" is not correct in standard written English.
It seems to be a misphrasing; the correct expression would typically be "a large role in" when discussing involvement or significance in a context.
Example: "She played a large role in the success of the project."
Alternatives: "a significant part in" or "a major role in".
Talent plays a large role of course, but so do curiosity, hard work and a knack for being in the right place at the right time.
The MK test also does not reveal a large role of positive selection in the evolution of proteins in hominids (Eyre-Walker 2006).
Studies of domestic homicide indicate a large role of alcohol, but homicide-suicide cases tend to have some other mechanism at play – as autopsies rarely find intoxication to be a factor (Rosenbaum 1990).
The views about the strong role of parents in this tradition (US, Canada, Australia) also argue for a larger role of the private sector.
This suggests a larger role of occipital cortex excitability in episodic migraine with aura and in chronic migraine compared to episodic migraine without aura.
Although the exact numbers will be different for Europe (expecting a larger role of dairy), the overall message will be similar: Cattle dominate the livestock footprint of both Europe and US".
The additional contribution of IL-10 in this mixture of Th1 and Th2 responses remains to be clarified, but may be critical in light of recent studies that highlight a larger role of IL-10 in HIV-1 pathogenesis.
Our approach for a larger role of HSV-2 subclinical ulcerations compared to GUD suggests that syndromic or episodic management of HSV-2 ulcers would have limited impact on reducing HIV incidence.
This suggests a larger role of polyuridylation in RNA metabolism in mammals, despite the fact that PUPs are mostly localized in the cytoplasm.
However, retrotransposition followed by intron gain is more likely at such a long phylogenetic distance, so we cannot rule out a larger role of retrotransposition in U12 intron removal.
The pollination experiments, however, point to a larger role of intrinsic incompatibilities, as opposed to ecological selection against hybrids, as the viable seed set for interspecific pollinations is lower than for intraspecific pollinations (Table 2).
