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It should be noted that the size difference between two radish mitochondrial genomes mainly arises from a novel sequence of 15,255 bp, not from a large repeated sequence.
The genome can be mapped as a 253,413 bp circle, but its structure is complicated by a large repeated region that is present in 6 copies.
During September 2009 (first week of term) through March 2010, we conducted a large repeated cross-sectional study analyzing pharyngeal swabs from students in all school-year groups at Nottingham University.
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The cluster on 8p23.1 contains eight beta-defensin genes of which seven (all but DEFB1) are on a large repeat that is variable in copy number.
Only 13 (1%) microsatellite motifs exhibited a large repeat number.
In DM1 the DMPK gene harbors a large repeat expansion in the 3' untranslated region [ 14– 16].
The Chrysochromulina tobin mitochondrial genome contains a large repeat region measuring 9.3 kb in length.
However, gaps can occur if reads that would typically be assembled into one contig cannot span a large repeat area.
A majority of familial frontotemporal lobar dementia and amyotrophic lateral sclerosis cases are associated with a large repeat expansion in a non-coding region of the C9ORF72 gene.
Within the mitochondrial genome, a large repeat structure consisting of ~9 kb was found along with a novel 457 amino acid open reading frame of unknown function.
Our Southern blot results provide evidence of recombination across a large repeat 4, and the in vivo co-existence of sub-genomic circles.
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