Hormone replacement therapy (HRT) is widely used with a large variety of regimens and medications.
A large variety of regimens have been demonstrated to be efficacious in the prevention and treatment of postanesthetic shivering, such as α2-agonist [ 4, 5], tramadol [ 1, 6], meperidine [ 7, 8], serotonin-3 receptor antagonist [ 9].
We can use the computational model to quickly and systematically test a large number of regimens and quantify improvements that are achievable, acknowledging two major obstacles: drug toxicity associated with increased cumulative exposure to antibiotics, and patient compliance and implementation issues associated with directly observed treatment.
The ability of the resulting thermomechanical model to simulate and, eventually, predict the shape storage and shape recovery of the material was evaluated against experimental shape memory thermomechanical torsion data in a large deformation regimen.
If we could observe T x for all participants and regimens, or if a large number of participants were randomized to each regimen x, then the optimal regimen x would simply be that which minimizes the AIDS/death risk across all participants–reflected, for example, by the probability of remaining AIDS-/death-free 10 years after baseline.
A large diversity of treatment regimens is another limitation.
A large variety of pharmacological regimens were proposed for the treatment or prevention of shivering.
Nevertheless, this study was a large comparison of NMA regimens among HCT recipients with LD.
This gave us the power to evaluate variation in a large variety of antibiotic regimens, across a large number of hospitals, in a large number of patients.
19 Although a large number of chemotherapy regimens have been proven in Phase III studies, there is no internationally accepted standard of care.
