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'a large opening' is correct and usable in written English.
You can use this phrase to describe something with a wide entrance or access, such as a doorway or a window. For example: "The old door of the abandoned cottage had a large opening that led out to the garden."
Exact(59)
An "open-bite" of the front teeth (a large opening between the upper and lower front teeth).
The internal opening is seen as a large opening into the dorsal aspect of anorectal junction (white arrow) Open image in new window Fig. 6 Sagittal T2-weighted image (a) and T2-weighted coronal image with fat-saturation (b) show an abscess (thick white arrows on a and b) at the level of anorectal junction.
There is a large opening in the stands behind the southern goal, behind which lies an open paved area.
One wall contained a large opening, like a doorway, with a pointed arch at the top.
"He had a large opening on his side, about 30 cm," he said.
"They had such a large opening for the radiator, at high speed, they'd tend to get a lot of lift.
A large opening between the laboratory and the front desk area enables visitors to see him at work.
Some rioters went to the back of the complex and knocked out a large opening in the brick wall.
Downstairs, under the sanctuary, there were archways and a giant marble pillar that rose up within a large opening in the ceiling.
Just beyond the cafe's glass facade facing Broadway there is a large opening in the sidewalk for a stairway to the subterranean No. 1 train platform of the 66th Street-Lincoln Center subway station.
Montreal planned to start dumping the sewage last month, in order for workers to relocate a snow chute – a large opening bringing water from melting snow to a wastewater treatment plant.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com