It would need a large initial loan but would later be self-financing, taking its expenses from proceeds recovered.
Medivation in turn licensed rights to Dimebon to Pfizer for a large initial payment of $225 million.
Such a large initial order book for the 787-10 suggesthatthat a bigger Dreamliner was overdue, analysts said.
The projects require a large initial fee of $200,000 to $600,000, depending on the size of the apartment, in addition to a hefty monthly rent.
The potential energy for the entire ride is usually introduced in a large initial climb that is converted to kinetic energy on the first and often sharpest drop.
Big software companies usually offer clients software for a large initial fee that enables them to use it for a year, followed by annual fees to continue using it and receive product upgrades and technical support.
A large, initial stretch of the story involves Jimmy's awkward reunion with his mother, who's happy to see him and angry that it's taken so long for him to visit.
While that amount is enough for a large initial advertising buy, it is sure to be only the first trickle in the total spent by candidate-focused super PACs in the coming months.
Although sometimes criticized for not creating any new wealth or products, eBay made it possible for members to run small businesses from their homes without a large initial investment.
Coulomb's chief executive, Richard Lowenthal, did not expect a large initial market; he said he would be thrilled if the company sold 100 of the approximately $40,000 chargers (which could require a $20,000 installation) in 2011.
This static model suggests a large initial employment probability disadvantage.
