The phrase "a large induction of" is not commonly used in written English and may sound awkward or unclear.
It could be used in contexts discussing significant increases or influxes, particularly in scientific or technical fields.
Example: "The study reported a large induction of new species in the ecosystem following the environmental changes."
Alternatives: "a significant increase in" or "a substantial influx of".
Its human ortholog, GK2, is strongly associated with male sexual development with a large induction of expression specifically in human testis-derived tissues.
When compared with the control diet, the consumption of chow lacking leucine leads to a large induction of TRB3 expression in the liver (Figure 1A) while a sharp decrease of leucine level (from 370 to 33 µM) was observed in the plasma (Figure 1B).
However, when these cells were treated with 10µM IDV, a large induction of eGFP expression was observed (Fig. 3B), thus validating the assay and the utility of eGFP as a biosensor for the inhibitory activity of antivirals, at least IDV, on PR in SupT1 cells.
We also observed a large induction of genes encoded within the cryptic plasmid, pJD1.
At a long term, a reduction in clonogenic capacity was observed, accompanied by a large induction of senescence.
During lactation there was a large induction of ERα with up to 70% of the nuclei positive at day 21.
This is perhaps best demonstrated by the large induction of the GPCR signalling pathway with a number of regulators of G-protein signalling (RGS) genes remaining up-regulated throughout the course of this study, suggesting the rate of GPCR signalling was increased [ 59].
Werner, S. et al. Large induction of keratinocyte growth factor expression in the dermis during wound healing.
Kester, M. H. et al. Large induction of type III deiodinase expression after partial hepatectomy in the regenerating mouse and rat liver.
However, if the severity is too large, induction of angiogenesis will only result in the depletion of energy stores and in the aggravation of brain damage.
The concurrent presence of atrazine and sucrose was associated with large induction of gene expression particularly related to cellular communication and signal transduction mechanism, detoxification and degradation of foreign compounds, oxidative stress responses, and protein degradation/cell aging.
