The phrase "a large impact when" is correct and usable in written English.
It can be used to discuss the significance or effect of an event or action that occurs at a specific time or under certain conditions.
Example: "The new policy will have a large impact when implemented across all departments."
Alternatives: "a significant effect when" or "a considerable influence when".
Hence, overlap between cohorts has a large impact when there is no vertical transmission, whereas the effect is much less dramatic in the presence of both vertical and cofeeding transmission.
When comparing data across platforms, the signal extraction or calibration techniques used had little impact on the correlations in the logarithm of the absolute intensity measure (Pearson correlations r were approximately 0.8), but had a large impact when correlating fold changes for the Illumina and Affymetrix mouse datasets (see Additional file 3).
Stochastic effects such as genetic drift have a larger impact when population size is small [ 17], as each stochastic death implies a larger change in the allele frequency distribution.
While a daily Diet Coke may seem small as sustainability sins go, curbing consumption could have a collectively large impact when you consider that 59percentt of Americans drink diet soda.
His former team's success will have a slightly larger impact when it comes to determining his donations to the athletic department.
Research efforts made in hemicellulose valorization at a laboratory scale can have large impacts when rolled out on a commercial scale.
Rayfield suspects that the skull had to absorb such large impacts when Allosaurus collided with its prey.
Mr. Raman says he thinks he has the largest impact when he can persuade other engineers to make their products accessible — or, better yet, when he can convince them that there are interesting problems to be solved in this area.
It appears that asset purchases have the largest impact when financial markets are frozen, so the Fed would need to buy larger quantities of securities to replicate the impact of its earlier purchases.
We consider the global CDI reconstruction method shown in Equation 5. Since the PA has the largest impact when α 1 = … = α N c [7], we will consider this worst case in the analysis.
