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This is consistent with a very long half-life and very high steady-state level of 18S, 5.8S/2S, and 28S rRNAs where changes in transcription affect the pool of rRNAs relatively little, and a low abundance of R1 and R2 transcripts where even small changes in transcription are seen as a large "fold" increase in RNA.
In humans, the major visceral AT depot corresponds to the greater omentum, a large fold of the peritoneum.
It is apparent that, despite a large fold change, the shapes of the peaks are very similar in the two cell lines.
In the current study, we also demonstrated a large fold change in Tnf mRNA abundance in small intestinal epithelial enriched extracts 1.5 hours after LPS administration.
In the present study we focused on GRIA2 because this gene had low P-values and displayed a large fold change.
2,076 transcripts were detected as significantly differentially expressed between the two sampling points using BaySeq and a cut-off posterior probability at 0.5, but among these transcripts only few showed a large fold change.
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Her scrapbook get-togethers, where friends buy supplies and work on their projects, involved a large folding table stored behind the loveseat and an elaborate rearrangement of furniture.
Almost three years later, Judge Barnes's courtroom remains a crime scene, its main door locked and shielded from view by a large folding screen.
Bones said police recovered a "large folding blade knife" from a nearby canal that is believed to be the weapon used in the stabbing.
A large fold-change value (|log2 fold change| > 5) was also used to identify DEGs.
The lower right- and left-hand corners of each graph contain the genes that showed a large fold-change but fail to achieve statistical significance (p > 0.01).
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CEO of Professional Science Editing for Scientists @ prosciediting.com