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One DMD patient presented with mental retardation associated with a large duplication of exons 65 79.
A large duplication of sequence between 7p14.3 and 7p15.1 was identified during the annotation of human Chromosome 7 [ 23].
Here we present evidence of a large duplication of the mitochondrial genome in the evolutionary history of the Sulidae.
Array-CGH analysis was conducted only for patient 4 and demonstrated a large duplication of near 34 Mb del 9p24.3-p13.3.
Evidence has been presented that genes in a large duplication of coding region in a scorpion fly (Order Mecoptera) were initially functional (Beckenbach 2011).
This is not only time-consuming but there is also evidence of a large duplication of work between those planning services for different localities in the same health areas [ 28].
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We found that the length of cam sequence is almost the same as that obtained from the physical map (219.7 kb vs. 218 kb), but because of a large duplication, the length of the ole mitotype is 360.3 kb, much larger than that previously reported from physical mapping (219 kb).
We found a large duplication in part of the mtDNA genome that was present and structurally identical in all three species.
No false-negatives or false-positives were identified among the re-sequenced loci; however resequencing of the apparent mutation at position 1486408revealed mixed genotypesin several isolates that are artifacts of a large duplication in the 1942 chromosome.
This study provides the first account of a large duplication event in T. brucei, which, if its consequences are similar to those in other organisms, may provide, or have provided, the raw material for evolutionary innovation and the expansion of gene families.
However, across the whole mt-genome, no vestige of such a large duplication was found.
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