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The phrase "a large drain on" is correct and usable in written English.
It can be used to describe something that consumes a significant amount of resources, such as time, money, or energy.
Example: "The new project has become a large drain on our budget, forcing us to reconsider our spending."
Alternatives: "a significant burden on" or "a heavy toll on".
Exact(5)
"I became ethical, and that caused a large drain on my energies.
With more than 160,000 American troops now in Iraq, the withdrawal in January of one brigade, roughly 3,500 to 4,500 troops, would not amount to a large drain on General Petraeus's forces.
"As we moved into early 2011 and the investigation launched, it became apparent there was going to be a large drain on resources from what is a valuable and finite resource, which is our detective capability," he said.
It is hard, Mr. DiVincenzo said, "to stay friends with the prosecutor's office," because it is such a large drain on county funds that are raised mostly through property taxes.
The costs of such plans need to be closely watched, however, since they can represent a large drain on the pension pot.Denmark gets around many of these difficulties with its collective DC system.
Similar(54)
In contrast, if processing the information across two images is a larger drain on attentional resources, degrading performance with each image (Rousselet, Fabre-Thorpe, & Thorpe, 2002; Scharff, Palmer, & Moore, 2011), inhibitory parallel processing would be observed.
However, almost half of the positive tests overall are, in fact, false positives (18/42=42.8%), which represents an unacceptably large drain on resources in the context of glaucoma and treatment of many other conditions.
A large drain was placed in the pericardial cavity.
Moreover, the government of Canada has been transparent about the costs and is fully accountable to its citizens.Lawrence Cannon Minister of foreign affairs OttawaSIR – I wonder if the cost estimates consider the full expense given the large drain on workers in Toronto from lost productivity and security measures.
Additionally, young people who are detained in justice systems offering little rehabilitation --compared to youth detained in more therapeutic and restorative programs are more likely to drop out of school, have diminished job prospects and become more reliant on public assistance, thereby creating an even larger drain on government coffers.
A standard computer screen is the single largest drain on power and the main reason laptops poop out after three hours of use.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com