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The phrase "a large downshift of" is correct and usable in written English.
It can be used when discussing a significant decrease or reduction in a particular context, such as performance, speed, or economic indicators.
Example: "The recent economic downturn has resulted in a large downshift of consumer spending."
Alternatives: "a significant decrease in" or "a major reduction of".
Exact(1)
A large downshift of prominent Raman active Г point LO mode phonons with an increase of vacancy concentration or decrease of ribbon widths are observed.
Similar(59)
A large downshift in the deposition position was observed at the high Te plasma.
We found that hyperglycemia induced a large downshift in the diaphragm contractile protein force-pCa relationship, reducing Fmax from 182.9 ± 1.85 kPa to 85.7 ± 1.99 kPa (this is an index of actin-myosin crossbridge formation) (P <0.001) and decreasing the coefficient of cooperativity, N, from 5.98 to 5.17 (P = 0.015).
The large downshift in class identity among young adults may have helped explain the surprisingly strong performance in Democratic primaries of the insurgent presidential candidate Bernie Sanders, who has promised to scrap college tuition fees and raise minimum wages.
Some day, quite soon, a large number of us might have to downshift - and that includes Gordon.
Under these circumstances, we would expect to observe a downshift of νC=C much larger than that observed (∼1 2 cm–1) upon titration from pH 7 to 2 (corresponding to only a 4 8 nm red shift in λmax) (see Figure S3 of the Supporting Information), in good agreement with the reported red shift for CaChR1 in detergent over the same pH range.
The obtained results also explain why we do not observe a clear downshift of the Raman frequency related to PC effect.
A slight downshift of the O 1s binding energy peaks is observed in the composite, implying the possible chemical bonding between Bi4Ti3O12 and Ag3PO4.
Interestingly, it can be noted that a small downshift of C=C peak is observed in BDMT/G as compared to pristine CVD-grown graphene.
A slight downshift of the monoglycosylated PrPC is also observed for brain homogenate after PNGase treatment (Figure 3).
In contrast, the conjugated enzyme was essentially stable at 25°C and underwent progressive destabilization on increasing temperature, suggestive of a substantial downshift of the stability optimum.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com