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A large disadvantage of cluster randomization is the risk of selective inclusion, i.e. the physician is more likely to discover to which treatment group all his or her patients are allocated and this might, unconsciously, play a role in selecting patients for participation in the study.
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So now it's Plotting and Betrayal Time at Jalapeno, which is already down to just five people, and about to become four, placing it at a large disadvantage come the merging of the tribes.
On the other hand, the largest disadvantage of the architecture is the massive size of calculation tasks that compare terribly to the computational power of today's processors.
One of the largest disadvantages of using a lattice model is that a large part of the molecular detail is lost in these models.
Secondly, it shows that there may still be a large mobility disadvantage among the fastest growing segments of workers, particularly in dense urban areas.
A high frequency of eating out and going on holidays among southwest French adolescents in the general population contributes to the large disadvantage found in such activities of southwest French adolescents with CP.
20 However, even slight disadvantages in terms of health can lead to large disadvantages in terms of employability during recessions, placing people at the back of a longer queue.
In this study, in order to overcome the aforementioned disadvantage, a large set of simulated ground motion records are used in a parametric study to examine the influence of different intensity measures on the energy-based response of simple structural systems, i.e. single-degree-of-freedom (SDOF) systems.
In spite of these limitations, our results highlight the very large survival disadvantage of children in the Philippines.
To address these disadvantages, a large amount of research has been done.
The advantage of a hole with smaller aspect ratio therefore comes with a disadvantage of a larger hole.
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