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The phrase "a large desk with" is correct and usable in written English.
You can use it when describing a desk that has specific features or items associated with it.
Example: "In the corner of the room, there was a large desk with a computer, books, and various office supplies."
Alternatives: "a spacious desk featuring" or "a big desk equipped with".
Exact(2)
She moved into his tiny studio on the Lower East Side, which at that time had three pieces of furniture: a large desk with a glass top, an uncomfortable modern chair and an uncomfortable bed.
Buy a large desk with lots of cabinets and drawers for storage.
Similar(58)
The immigration lawyer is sitting behind a large desk cluttered with Home Office papers and folders, piled on top of each other in precarious towers.
The guards brought us to a clean, modern office with a large desk and couches along the walls.
But inside the complex, where 8 full-timers work, Usher's office is spartan, with a large desk, a black velour sofa, dim lighting and a couple of remote-controlled toy Porsches shoved into the corner.
There was a large desk a few feet away, piled with papers, sketchbooks, magazines, books, newspapers, and art supplies.
Each of the 339 guest rooms comes with high-speed Internet access, a large desk and a silent fax.
Dressed in a black T-shirt with the word "witness" across the front, he opened his laptop at a large desk in the living room.
Take a large desk dictionary (not a pocket version).
A large desk and maybe a bookshelf is required.
Spread the cases out on a large desk or table.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com