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This result suggests that VEP does a better job at reporting when the transcript it uses for annotation is non-coding, but that there may actually not be such a large degree of difference between splicing annotations as appears initially.
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We caution, however, that all of these comparisons have a large degree of uncertainty because of differences between the studies and ambiguities in the definitions of the target populations.
In spite of a large degree of conservation between teleost TLRs and their mammalian orthologues, there are some differences in signalling and their ability to recognise PAMPs [ 4].
While essential differences exist between the two organisms, a large degree of conservation is also present.
Based on our previous analysis, 4 we anticipated a larger degree of variation and heterogeneity in the overall effect estimates between studies because of different study designs, methods of analysis, different exposure lags, and geographical and population differences.
The parasite genome is diploid but displays a high degree of difference between homologous chromosomes.
The difference observed between these assays is probably, to a large degree, due to differences in the ELISA format, to higher antibody affinity, to better amplification of the detection signal, and to improved assay standardization.
What is clear is that in politics there's only a degree of difference between building bridges and burning them.
To a large degree, it read like the difference between a kludge and a normal policy is the level of government policy.
Antagonism between the main parties - the Awami League and Bangladesh Nationalist Party - to a large degree reflects personal animosity between leaders rather than substantial ideological differences.
Thus small differences in transcript levels may manifest themselves in large differences in protein levels and vice versa, which may also be an explanation for the relatively large degree of discordance between transcript and protein profiles.
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