The phrase "a large defect" is correct and usable in written English.
It can be used to describe a significant flaw or imperfection in something, such as a product, design, or system.
Example: "The quality control team identified a large defect in the manufacturing process that needed immediate attention."
Alternatives: "a major flaw" or "a significant imperfection."
A large defect with exposed pericardium and great vessels was found post resection in both cases.
Type IV hiatus hernia is associated with a large defect in the phrenoesophageal membrane, allowing other organs, such as colon, spleen, pancreas, and small intestine to enter the hernia sac (Figure 14). Figure 13: Type III paraesophageal hiatal hernia.
Conclusions: Despite the risk of wound complications, this method is particularly useful for complex sinuses with extended tracts where radical excision leaves a large defect.
By modifying the traditional surgical technique and post-operative care, we were able to design a pedicled fascio-cutaneous ALT flap to cover a large defect in the epigastric region.
Based on a previous clinical case report in which the pedicled subcostal artery perforator flap allowed for the closure of a large defect of the lumbar region, the present study was designed to investigate the anatomy of the subcostal artery perforator flap and to evaluate its potential for wider clinical use.
The destructive test shows a large defect in area a in this seam section.
The near infrared (NIR) responsivity decreases with temperature in devices with a large defect-density, but is more stable in high-quality photodiodes.
A larger defect could have prevented the endogenous healing in the empty defect control group.
Two advancement flaps may be fashioned from either side to cover a larger defect over the anteromedial tibia.
But President Obama's vision for a new era of "middle-class economics" suffers from a larger defect: there's a fundamental mismatch between the President's spending programs and his tax proposals.
Our results suggest that a lack of the soxS gene results in a larger defect in resistance to superoxide than the lack of a soxR gene.
