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The phrase "a large decrease of" is correct and usable in written English.
It can be used when discussing a significant reduction in quantity, size, or degree of something.
Example: "There was a large decrease of sales in the last quarter compared to the previous one."
Alternatives: "a significant drop in" or "a substantial reduction in".
Exact(46)
This dilution, and the resulting viscosity increase, results in a large decrease of the Brillouin gain that can largely compensate the effect of Raman gain decrease due to the lower concentration of Raman active molecules in the mixture. .
The main phase is characterized by a large decrease of Dst (Gonzalez et al., 1994).
This could result in a large decrease of the overall system throughput.
LOAD, however, resulted in a large decrease of HLRC after correction for slope (Fig. 7c).
This process is accompanied by a large decrease of surface area.
Results on static drop show a large decrease of spurious currents compared to other methods.
Similar(13)
A higher electric field at the same process temperature produced a larger decrease of E. coli.
It provided a larger decrease of mitochondrion membrane potential and induced cellular apoptosis.
Use of the stop-word lists hardly affects recall, with a largest decrease of only 1.1% for PubChem.
The decrease of shell thickness leads to a decrease of maximum internal pressure and a larger decrease of critical cracking pressure, which will increase the risk of shell cracking.
Therefore, it may be possible that for the presently studied case, there was a stronger negative contribution existing in the same direction as that due to the magnetopause currents during daytime and which may therefore have resulted in a larger decrease of the H component.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com