The phrase "a large decrease in the number" is correct and usable in written English.
It can be used when discussing a significant reduction in quantity or figures, often in contexts like statistics, economics, or research findings.
Example: "The recent report indicated a large decrease in the number of participants in the study compared to last year."
Alternatives: "a significant drop in the number" or "a substantial reduction in the number."
The fall in 2014 also reflects a large decrease in the number of grants of settlement (permanent residence) which created a smaller pool of newly eligible applicants for citizenship.The disparity in the cost of naturalisation between countries is stark (see chart), reflecting in part differing views of the costs and benefits of citizenship.
We observed a large decrease in the number of conserved human CG junction exons from chimpanzee to macaque and orangutan.
In the adrenal medulla of these mice there was a large decrease in the number of secretory granules; in addition it was noted that the secretory granules present appeared to be swollen.
Using cell type-specific markers, we found that there was no change in the number of ciliated cells or goblet cells, but there was a large decrease in the number of SSCs (61% reduction; Fig. 5B).
It also caused a large decrease in the number (P < 0.001) and surface area (P < 0.01) of gamma-glutamyltranspeptidase (GGT -positive hepatocyte foci and in the labellinGGT -positive0.001) of focal cells, coupled withepatocyted (P < 0.01) remodelling.
Within hypoxia-treated MDA-MB-468 cells, inhibition of HIF1α with the small molecule inhibitor CAY10585 or transfection with siRNA targeting HIF1α caused a large decrease in the number of vimentin-negative cells.
The fitted model indicates a large decrease in variability of lead concentration as pellet numbers increased.
A sharp decrease in the number density coincides with clearing a large surface area.
Elementary schools registered the largest improvement, with a collective 24 percent decrease in the number of absences.
Bloomberg's tenure was marked by an expansion in charter schools, a decrease in the number of teachers who earn tenure, and the closure of large campuses to make way for smaller schools -- often located in the same building.
The second peak is not detectable due to a decrease in the number of large diameter hairs (Figure 2B).
