Sentence examples for a large clinical problem from inspiring English sources

The phrase "a large clinical problem" is correct and usable in written English.
It can be used when discussing significant issues or challenges faced in a clinical or medical context.
Example: "The rise in antibiotic resistance has become a large clinical problem that healthcare providers must address."
Alternatives: "a significant clinical issue" or "a major clinical challenge".

Exact(3)

Neuropathic pain is a large clinical problem, not least such pain affecting lower extremities.

The possibility of such transfer may not imply that when it occurs, it will lead to a large clinical problem.

The lack of validated animal models of SIDS is puzzling given that this is a large clinical problem with little mechanistic insight at the moment.

Similar(57)

This response is in some contrast to the general perception that morning fatigue is a much larger clinical problem than fatigue during the day in patients with AI who have low or undetectable serum morning cortisol levels when using hydrocortisone BID or TID.

It is awaiting results of a large clinical trial.

Lilly will begin a larger clinical trial for the drug this month.

Toward that end, a larger clinical trial is underway.

Abnormal channel activity can contribute to the development and maintenance of painful neuropathies, which pose a large and persistent clinical problem [ 1].

We found that, despite modern nutritional management, rickets is a common clinical problem in a large NICU setting.

Luciana Mascia, Eleomore Corno and Pier Paok Terragni Although the need for and optimal timing of tracheostomy for brain-injured patients is a common clinical problem, no large randomized trials have unequivocally clarified whether this intervention improves outcome.

Constitutive and acquired resistance to EGFR inhibitors in a large number of patients is a relevant clinical problem.

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