Sentence examples for a large cleavage from inspiring English sources

A large cleavage product (∼110 kDa) was generated (Figure 2).

The polyA tail is added at the polyA site (PAS) in the nucleus in a 2 two-step reaction consisting of a large cleavage complex that cleaves the pre-mRNA into two fragments followed by polyA tail addition to the upstream fragment [ 25].

This RNA cleavage reaction is mediated by an endonuclease (CPSF73) that is part of a large multimeric cleavage and polyadenylation complex.

Large cleavage facets were observed for the β-annealed Ti64 specimen with dimples intermittently located in between these facets.

Although this approach fails in part of the cases (9.6% of slices) to fill-up the ventricular or atrial cavities (e.g. if the myocardium has tears, particularly large cleavage planes, and/or is very thin as in parts of the RV), defective slice segmentations can be visually identified with ease and removed.

There was also a large decrease in cleavage at the double-strand cleavage site closest to the site of methylation (C13/G52, 10 to 2% for the 5′-end-labeled DNA and 9 to 2% for the 3′-end-labeled DNA) with a large increase in double-strand cleavage at the site most distant from the site of methylation (T10/A55, 2 to 6% for both end-labeled DNAs).

We judged spots with methylation changes using two models; one in which spots with methylation changes had different values for Hpa II and Msp I cleavage, and the other in which spots with methylation changes had a large Hpa II cleavage difference (more than 5) and a small Msp I cleavage difference (less than 2).

TEV is translated into a large polyprotein, thus the cleavage process may be a mechanism to regulate the effective concentration of viral proteins in infected cells (Merits et al. 2002).

After cleavage, a large fragment containing amino acids 1 to 43 is formed, which is termed N-MID because it contains the amino (N -terminus aN -terminusortion of the protein.

In this paper we have opted to use the C-terminal amino acid of CTL epitopes to position an epitope in a protein sequence, as the C-terminal amino acid is the most defining property of an epitope: amino acid substitutions at the C-terminal have a large effect on proteasomal cleavage, TAP transportation and MHC binding [ 23, 24] (Fig. 1).

It is worth bearing in mind that the substrate of Cas6 is a large pre-crRNA with many cleavage sites and that two RNA-cleavage events are required to generate one unit-length crRNA.