The phrase "a large blow" is correct and usable in written English.
It can be used to describe a significant impact or setback, either physically or metaphorically.
Example: "The company suffered a large blow when their main product was recalled due to safety concerns."
Alternatives: "a significant hit" or "a major setback."
In the piece, Clegg talks of the friendliness and hospitality he finds in Wales – but how Tory and Labour governments have dealt the country a large blow with the recession.
So far, Mr. Stiso has had to give up representing 18 defendants in the Manhattan Federal Court, said his lawyer, Mr. Richman, a large blow to a legal practice Mr. Stiso has carefully built up since 1990.
In a large blow to the Serious Fraud Office, five of the six brokers accused of helping Tom Hayes – who is serving 11 years in prison – to rig Libor have been cleared.
The growing frustration with the government in Khyber-Pakhtunkhwa this weekend is a large blow to Islamabad, which is often criticized for being disconnected from the needs of the people in the province, which represents a pivotal battleground against the Islamic insurgency.
The tensions have prompted four Arab countries — Qatar, Bahrain, Kuwait and the United Arab Emirates — to warn their citizens not to travel to Lebanon, which could deal a large blow to the pending summer travel season, a main engine of Lebanon's economy.
Based on the presentations, Apple TV+ appears to be a large blow against reality TV and low-brow entertainment.
Each physical fragment of texts is reproduced twice, once at actual size and once in a large blow-up several feet wide, and the texts are transcribed and translated beside them, in German and English.
"It's a 'bring your pet and do it yourself' or a 'call your groomer' space," Ms. Frumkes says of the spotless tiled room equipped with a large blow-dryer table and a deep stainless-steel sink.
Take the unreadable game cartridge and blow a large puff of compressed air on the back of the cartridge where the metal is.
Although debarment is rare, he said, "that could be a very large blow both to reputation and to business BP does with the federal government".
A decline in employee retirement revenues, which includes earnings on investments and contributions, dealt a particularly large blow to revenue figures for state and local governments.
