The phrase "a large benefit of" is correct and usable in written English.
It can be used when discussing the advantages or positive aspects of a particular subject or action.
Example: "One large benefit of regular exercise is improved mental health."
Alternatives: "a significant advantage of" or "a major benefit of".
A large benefit of this design is that buildings can recover waste heat from each other directly.
Reisinger discovered that a large benefit of teaching in the Link came from the flexibility offered by the ability to bring technology in and out of the classroom as needs be.
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This may be particularly important in complementary medicine, in the presence of high heterogeneity between trials, and when pooled effect sizes indicate a large benefit of evaluated interventions.
When 100% of patients had wild type EGFR, the model suggested that there is no difference in PFS with TKIs compared with no active treatment (HR, 0.95; 95% CI, 0.65-1.38; P =.78), whereas when 100% of patients had EGFR mutations, a large benefit of TKIs was indicated (HR, 0.12; 95% CI, 0.02-0.66; P =.015; Figure 5).
Since pulmonary vasocontriction is an early and partially transient phenomenon in acute pulmonary embolism [ 14], this might explain why animal models show a larger benefit of vasodilator treatment.
We found a larger benefit of ipilimumab for those patients who received SRS, but we did not have adequate power to determine whether this interaction was statistically significant.
However, patients carrying the 'AA' genotype in the CYP2R1-gene, encoding the 25-hydroxylase enzyme, had a larger benefit of vitamin D3-supplementation (–55%) compared to AG or GG carriers (–6%) (n=124, p=0.046 for interaction, see online supplementary table S6).
The above suggests that any preventive benefit of tamoxifen in women positive for the high risk BRCA1 mutation is likely to be modest, but that a larger benefit of the order of a 25 35% reduction in incidence may be conferred in BRCA2 mutation carriers.
Although the exact mechanism by which smoking might enhance the activity of antiplatelet agents is not known, five out of the six studies in our analysis that compared clopidogrel with control arms found a larger benefit of clopidogrel in smokers than nonsmokers.
"Getting a large benefit for lots of people that didn't exist before is very alluring," said Senator Charles E. Schumer, Democrat of New York.
