Protein aggregation in cells is emerging as common features of the diseases, in particular for a large array of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and prion diseases.
Finally, our present success again highlights the promising potential to use salt-free water to solubilize various previously thought insoluble proteins for high-resolution biophysical investigations to better understand mechanisms for protein folding and aggregation responsible for a large array of human diseases [1] [4], [68] [70].
Artemisinins are demonstrating vast therapeutic potential for a large array of different diseases.
Immature technologies still in the process of having their clinical place and relevance defined, are often proposed for a variety of clinical indications and the literature reports a large array of patients, diseases and outcomes [ 9].
Research has shown that SRH is determined by a large array of factors, such as chronic disease conditions, genetic markers (e.g., Apolipoprotein E, APOE, NM_000041), stress factors, and health behaviors.
However, there is a vast quantity of information and data sources available currently, and it is expected that a tool with the flexibility to include a large array of data sources would positively aid disease gene discovery.
CVID is a complex, multifocal disease with a large array of clinical manifestations and complications.
Understanding the fundamental regulatory mechanisms of tissue morphogenesis has implications for a large array of biological problems, ranging from congenital heart disease [ 1] to tumorgenesis [ 2].
Displaced populations in camp settings are at high risk of infectious diseases owing to a large array of risk factors including inadequate shelter, overcrowding, inadequate quantity and quality of food, poor sanitation, poor personnel hygiene, economic and environmental degradation, compromised heathcare practices, and movement of people from areas of low to high endemicity [ 16].
To our knowledge, this is the first study to examine such a large array of inflammatory SNP markers in association with trachomatous disease.
