This requires a high demagnification to permit the use of larger object apertures giving lower slit scattering, but this usually results in a correspondingly large aberration.
Microarrays affected by a very large aberration should be removed from the study, as they no longer serve as a reliable source of information.
Furthermore, LAD-aFL significantly improves the estimation of the relative intensities for all large aberrations.
To meet the requirement of large aberration measurement, a multi-level Box Behnken design approach is tested in conjunction with AMAI-PCA to build the aerial image space.
This might be due to imperfect modelling of the corresponding region of the tissue, or to measurement uncertainty due to large aberration values as discussed in section 3.
Compared with wild types (M = 39.24, SD = 33.19), the initial goal approaches of Ccnd2−/− mice had a significantly larger aberration from the straight start goal connection (M = 94.56, SD = 70.97), whereas the heterozygotes did not show differences from wild types.
A comparison with previously reported large aberrations is shown in Table S5.
As expected, all platforms were able to detect large aberrations in a robust manner.
As expected, all platforms were able to identify large aberrations in a robust manner.
When compared to the 2102Ep teratocarcinoma line in the CGH assay, CH-ES1 displayed two common large aberrations, namely, duplication in 5q34 and a deletion of 13q32.1-q34 (Table 2).
