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The Washington Post labelled the announcement a "landmark"; Time called it "historic".
This is a landmark time to work in the field of robotics and to be able to reflect on our progression from lab project to marketplace.
As we defined a landmark time of 2 days, these patients were referred for 'late' revascularisation after ACS.
17 In our study, we defined a landmark time of 48 h; thus, we missed the earliest occurrence of coronary events and the associated predictor power of troponin.
At a landmark time of 6 months, the model showed a statistically significant difference in EFS between patients classified as slow (monophasic) and fast (biphasic) responders.
A landmark time of 4 months was selected as the majority of EPP procedures were performed within the first 4 months.
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For survival time data, this requires that survival time must be converted to a binary endpoint at a prespecified landmark time, for example, patient alive at five years.
We predicted each patient's event status by whether the BCR-ABL1 levels were above or below a particular threshold at a particular landmark time.
In addition, the landmark method [ 16] was used to estimate survival after an IBTR; the landmark time of 1.7 years since surgery was chosen because half of the 14 women who had both outcomes had experienced an IBTR by this time.
A retrospective landmark time-point analysis in the BMS099 trial [ 2] and a pre-specified subset analysis in the FLEX [ 7] trial demonstrated better outcomes for patients who developed rash by the end of cycle 1 with cetuximab added to front-line therapy.
The intention of the landmark method is to estimate in an unbiased way the time-to-event probabilities in each group conditional on the group membership of patients at a specific time point, the landmark time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com