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The article assumes the linear mixture model (LMM) of the background and a known target signature.
If an observation cannot be associated with a known target, a new tentative filter is initialized.
Position accuracy was individually measured in both arms and compared to a known target position.
GBSS, a known target gene of OsSMF1, was also identified in our analysis (Wang et al. 2013).
The authors demonstrate that protein-ligand fingerprints outperform the corresponding ligand fingerprints in predicting either putative ligands for a known target or putative targets for a known ligand.
This suggestion converges with research examining wayfinding to a known target, which implies that planning the entirety of a route can occur before beginning a journey (Allen, 1999).
Their potency were evaluated in an enzyme inhibition assay against rabbit muscle glycogen phosphorylase a (RMGPa), a known target protein of oleanolic acid.
Most computational techniques for the design of combinatorial libraries have concentrated solely on maximizing the diversity of the selected subset or its similarity to a known target.
Rational approach to drug design is the process to find new potent molecules on the basis of a known target and available ligands for the target.
Charlie Hebdo, a satirical magazine known to militants that despised the published pictures of the Prophet Muhammad, was in fact a known target.
p38 MAP kinase is also a known target for other PDE inhibitors such as pentoxifylline [63].
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CEO of Professional Science Editing for Scientists @ prosciediting.com