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The p73 structure exhibits the same conserved architecture as p53 but displays a divergent L2 loop, a known site of protein protein interaction.
PEG-HCCs were not internalized by immune cells in the inguinal lymph nodes (Fig. 1b, right), although they could be observed in the intact tissue (Supplementary Fig. S4), suggesting PEG-HCCs may not remain in the lymph nodes sufficiently long enough to be internalized by T cells, unlike in the spleen, a known site of PEG-HCC accumulation25.
Although archaeology was a long-held interest, his devotion to rock art began after he uncovered an unrecorded example two metres from a known site: "I suddenly realised that all these things hadn't been recorded and hadn't been discovered … I made a determined effort to find some more".
Vertebral osteomyelitis should be considered in febrile SCI patients, even in a patient with a known site of infection [53].
beta-Arrestin2 facilitates ANG and SII stimulation of Src-mediated phosphorylation of Tyr-845 on the EGFR, a known site for Src phosphorylation.
For ICU patients who have nonbacteremic sepsis from a known site of infection, antibiotics can be stopped if the PCT level at day 3 is < 0.5 ng/mL or has decreased by >80% relative to the highest level recorded, irrespective of the severity of the infectious episode; in bacteremic patients, a minimal duration of therapy of 5 days is recommended.
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Ek' Balam, until now a lesser known site, is fast becoming a popular stop on the tour circuit.
PhosphOrtholog also successfully mapped all known sites reported in PhosphoSitePlus, thus reporting a "known site enrichment" rate of 100%%.
"a" is the known site in the known protein.
Neither SNV allele occurred in a CpG dinucleotide; the only known site with an increased propensity for de novo mutations [ 10] (see Additional file 3, Table S2).
Upward Sun River is the only known site with a cremation inside a house, Potter says.
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