The phrase "a known functional" is correct and usable in written English.
It can be used in contexts where you are referring to a functional element or aspect that is already recognized or established in a particular field or discussion.
Example: "In this study, we will analyze a known functional that has been previously identified in the literature."
Alternatives: "an established function" or "a recognized functional".
For those genes implicated in the experimental dataset that did not have a known functional product, in silico annotation was undertaken to predict a function.
Most works reported in existing literature have been based on the assumption that the probabilistic properties and statistical parameters have a known functional form, which is usually not the case.
Only six patients (17% of survivors with a known functional status) required admission to a long-term care facility.
As second step, we evaluated whether the novel motif in the context of miRNA target sites has a similarity to a known functional motif.
In one world-view, if adaptive evolution implies functional divergence, such divergence might be more likely to occur in a known, functional domain.
We hypothesized that a known functional polymorphism in the promoter of the NFKB1 gene may affect susceptibility to and outcome from ARDS.
The od22 mutation alters the conceptual translation of RPM-1 protein from arginine to an Opal stop codon at amino acid 30, resulting in a protein lacking all known functional domains (Fig. 2A).
The Nectria haematocca protein does not have a PfamB_2311 domain or any known functional domain.
A complete list of all known functional human variants in the collagen VI genes is compiled at the Leiden Muscular Dystrophy pages (http://www.dmd.nl/).nl/
A third known functional element that was detected as a significantly conserved stretch is SL4 [ 32, 33], which serves as part of the RNA packaging signal and is located in gag (Stretch 15 in Table 2).
Network-based learning algorithms for automated function prediction (AFP) are negatively affected by the limited coverage of experimental data and limited a priori known functional annotations.
