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In particular, the Ub-binding ZnRs associated with the MABP domain in at least two proteins have been found to bind monoubiquitin, a key trafficking signal (Raiborg and Stenmark, 2009).
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With 750 million users Facebook is already the world's biggest photo website and a burgeoning platform for video, gaming and television – a key traffic driver for media owners, offering specifically targeted advertising and interaction.
The marker used to measure the impact of the traffic due to expansion is black carbon (BC), a key traffic related emission mostly associated with large vehicles (>12 m in length), collected both before and after the expanded lanes were open for use.
Prevention activity focused on Edo state, as Nigeria's key trafficking hub, must be a core focus of the government's new fund.
DOI: http://dx.doi.org/10.7554/eLife.04535.002 Clathrin-mediated endocytosis is a key membrane trafficking process for the uptake of cargo molecules from the cell surface.
Antagonists that bind to the 7TM site display striking differences in their impact on this key trafficking step.
Using cell lysates extracted in the presence of 1% Triton X-100, we performed co-immunoprecipitation analyses to identify potential interactions between GPR177 and key trafficking regulators.
This model captures a set of key traffic characteristics for each pair of regions in the entire urban network, including travel demand, travel speed and route directness of travel paths.
The effort became even more complicated later in 2006, when Benjamin Freakley, the two-star U.S. general who ran the eastern front, shut down all operations by the D.E.A. and Afghan counternarcotics police in Nangarhar — a key heroin-trafficking province.
Taken together, results of this study demonstrated that the "TβII > TβI > R-Smads > PKA" pathway mediates TGFβ3's anti-motility signaling in HDFs, which represents a key cells traffic regulator during wound healing.
The scheme is one of dozens of projects nationwide approved by the government under plans to ease congestion on key traffic "pinch points".
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