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The phrase "a key reason is" is correct and usable in written English.
You can use it to introduce an important explanation or justification for a statement or argument.
Example: "A key reason is the significant impact of climate change on global weather patterns."
Alternatives: "a primary factor is" or "an important reason is".
Exact(39)
A key reason is European politics.
A key reason is cost.
A key reason is that it works better aesthetically.
A key reason is the connection between selection and moral hazard in star hospital use.
A key reason is that Asians living in Britain maintain an immigrant mentality towards sport.
A key reason is that while foreign investment surged, domestic investment in Mexico dipped.
Similar(21)
A key reason was fear, Dougan and others said.
A key reason was "a thinning of an informed, engaged, independent centre of our polity".
A key reason was that individuals' engagement varied highly significantly during the lecture.
According to Jeffrey Clemens, an economist at the Stanford Institute for Economic Policy Research, a key reason was New York's aggressive expansion of Medicaid to cover the "medically needy," which drew in more relatively unhealthy New Yorkers.
A key reason was Erdogan's provocative insistence on transforming the presidency from a largely ceremonial position to a strong executive post.
More suggestions(3)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com