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The phrase "a key problem is that" is correct and usable in written English.
It can be used to introduce a significant issue or challenge that needs to be addressed in a discussion or analysis.
Example: "In our research, a key problem is that the data collected was insufficient to draw meaningful conclusions."
Alternatives: "a major issue is that" or "a significant challenge is that".
Idiom
Problem is thirty.
If a problem is 30, the problem is the person who sits 30 cm from the computer screen.
Exact(14)
But a key problem is that species need to be preserved for reasons other than any known value as resources for human use (Sober 1986).
A key problem is that local governments frequently build budgets upon inaccurate revenue forecasting, he said.
A key problem is that the optimal input depends on system parameters to be identified.
A key problem is that laws established at the level of observation and experiment involve or imply properties other than the primary ones of the mechanical atomist.
"A key problem is that the department has been unable to create a competitive market for medical assessment providers, leaving Atos in the position of being a near monopoly supplier," she said.
And, as Oliver pointed out, a key problem is that, the New York arrests aside, often these practices remain legal.
Similar(46)
The key problem is that BT hasn't put the money into it because it hasn't been forced to.
Ramos thinks that the key problem is that observers feel isolated and disempowered by the European Commission and the national authorities, and should get better backup from inspectors.
The reality, however, is that many hurdles still have to be overcome first.One key problem is that of connecting the implant, which is inserted into the eye, with the patient's nervous system.
The purpOne of this letter isn't to send everyone off in a panic.
The key problem is that information obtained from the information service may be outdated by the time the scheduler needs it to schedule tasks.
More suggestions(17)
a key concern is that
a key point is that
a key assumption is that
a key reason is that
a key risk is that
a key corollary is that
a key similarity is that
a key message is that
a further problem is that
a key attraction is that
a realistic problem is that
a key answer is that
a key one is that
a key difference is that
a key aspect is that
a key contribution is that
a key thing is that
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com